Reaching trans women in San Francisco for efforts to eliminate hepatitis C

J Viral Hepat. 2021 Sep;28(9):1325-1328. doi: 10.1111/jvh.13521. Epub 2021 May 3.

Abstract

Hepatitis C infections continue to rise among marginalized communities, including among transgender people. Efforts to eliminate hepatitis C from San Francisco require successful identification of active HCV infections among transgender women and subsequent treatment of infection. This secondary analysis of the National HIV Behavioral Surveillance Transgender Women (NHBS-Trans) Study aims to identify areas of improvement in the hepatitis C care cascade and associated barriers that preclude successful treatment. One hundred and eighty (89.6%) trans women reported being previously screened for HCV, 47 (26.1%) reported being diagnosed with HCV, twenty-eight of the 47 (59.6%) who reported HCV diagnosis also reported that they received HCV treatment, with and 24 of the 28 (85.7%) reported completing their treatment. Overall, we detected HCV antibodies among 23.9% of participants and detected HCV RNA among 6.0%. This suggests that despite improvements in screening for HCV, active cases may not be successfully treated. Efforts to reduce barriers to HCV care should be prioritized, with heightened consideration for trans-specific needs.

Keywords: HCV cascade; hepatitis C virus; injection drug use; transgender.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Female
  • HIV Infections* / epidemiology
  • Hepacivirus / genetics
  • Hepatitis C* / diagnosis
  • Hepatitis C* / drug therapy
  • Hepatitis C* / epidemiology
  • Humans
  • San Francisco / epidemiology
  • Transgender Persons*