The evolution of intracranial aneurysm treatment techniques and future directions

Neurosurg Rev. 2022 Feb;45(1):1-25. doi: 10.1007/s10143-021-01543-z. Epub 2021 Apr 23.

Abstract

Treatment techniques and management guidelines for intracranial aneurysms (IAs) have been continually developing and this rapid development has altered treatment decision-making for clinicians. IAs are treated in one of two ways: surgical treatments such as microsurgical clipping with or without bypass techniques, and endovascular methods such as coiling, balloon- or stent-assisted coiling, or intravascular flow diversion and intrasaccular flow disruption. In certain cases, a single approach may be inadequate in completely resolving the IA and successful treatment requires a combination of microsurgical and endovascular techniques, such as in complex aneurysms. The treatment option should be considered based on factors such as age; past medical history; comorbidities; patient preference; aneurysm characteristics such as location, morphology, and size; and finally the operator's experience. The purpose of this review is to provide practicing neurosurgeons with a summary of the techniques available, and to aid decision-making by highlighting ideal or less ideal cases for a given technique. Next, we illustrate the evolution of techniques to overcome the shortfalls of preceding techniques. At the outset, we emphasize that this decision-making process is dynamic and will be directed by current best scientific evidence, and future technological advances.

Keywords: Aneurysms; Clipping; Coiling; Endovascular embolization; Flow diversion; Stents; Subarachnoid hemorrhage.

Publication types

  • Review

MeSH terms

  • Embolization, Therapeutic*
  • Endovascular Procedures*
  • Humans
  • Intracranial Aneurysm* / surgery
  • Microsurgery
  • Retrospective Studies
  • Stents
  • Treatment Outcome