Couples After Renal Transplantation: Impact of Sex and Relationship Quality on Adherence in a Prospective Study

Transplant Proc. 2021 Jun;53(5):1599-1605. doi: 10.1016/j.transproceed.2021.02.017. Epub 2021 Apr 20.

Abstract

Background: In patients after kidney transplantation, nonadherence to immunosuppressant medication is a common problem. Identifying factors that influence adherence could optimize medical care and prevent nonadherence. Kidney transplantation is a stressful situation for the patient and also for the relatives. The recipients of renal transplants as well as the family system have to be taken into account as potential impact factors.

Methods: Fifty-six couples with a renal transplant recipient were investigated regarding adherence, relationship satisfaction, social support, and quality of life. Moreover, sex and role differences (patient vs partner) as well as differences within the couple were analyzed. Impact factors on adherence were identified.

Results: Female recipients of renal transplant reported higher relationship satisfaction than male recipients, female spouses, and male spouses. Physical quality of life was lower in renal transplant recipients compared with caregivers. For male renal transplant recipients, significant predictors of adherence, such as social support, relationship quality, and quality of life emerged, whereas for female renal transplant recipients mental quality of life and education level were found to influence adherence.

Conclusions: The study reveals the importance of relationship functioning of couples after kidney transplantation, as well as considering sex and role differences. There is a need to examine the posttransplantation nonadherence risk profile of women and men separately.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Cross-Sectional Studies
  • Family Relations
  • Female
  • Humans
  • Immunosuppressive Agents / therapeutic use*
  • Kidney Transplantation*
  • Male
  • Medication Adherence / statistics & numerical data*
  • Middle Aged
  • Prospective Studies
  • Quality of Life
  • Sex Factors
  • Social Support
  • Spouses
  • Transplant Recipients

Substances

  • Immunosuppressive Agents