Early to beta and neuronally precocial makes a mouse have weak gamma and be less social

Daniel C Lowes; Alexander Z Harris

doi:10.1016/j.neuron.2021.03.036

Early to beta and neuronally precocial makes a mouse have weak gamma and be less social

Neuron. 2021 Apr 21;109(8):1250-1252. doi: 10.1016/j.neuron.2021.03.036.

Authors

Daniel C Lowes¹, Alexander Z Harris²

Affiliations

¹ Department of Psychiatry, Columbia University, College of Physicians and Surgeons, New York, NY 10032, USA.
² Department of Psychiatry, Columbia University, College of Physicians and Surgeons, New York, NY 10032, USA; Division of Systems Neuroscience, New York State Psychiatric Institute, New York, NY 10032, USA. Electronic address: ah2835@cumc.columbia.edu.

PMID: 33887190
DOI: 10.1016/j.neuron.2021.03.036

Abstract

In this issue of Neuron, Bitzenhofer et al. show that transiently stimulating the prefrontal cortex during a brief critical window early in development causes precocious maturation and lasting deleterious consequences on circuit activity and behavior.

Publication types

Comment

MeSH terms

Animals
Cognitive Dysfunction*
Mice
Neurons
Prefrontal Cortex*