Isogenic human pluripotent stem cell disease models reveal ABRA deficiency underlies cTnT mutation-induced familial dilated cardiomyopathy

Protein Cell. 2022 Jan;13(1):65-71. doi: 10.1007/s13238-021-00843-w. Epub 2021 Apr 22.

Bin Li^#^{1

2}, Yongkun Zhan^#¹, Qianqian Liang^#^{1

3}, Chen Xu^{1

3}, Xinyan Zhou¹, Huanhuan Cai¹, Yufan Zheng¹, Yifan Guo¹, Lei Wang⁴, Wenqing Qiu⁴, Baiping Cui¹, Chao Lu^{1

3}, Ruizhe Qian^{1

3}, Ping Zhou¹, Haiyan Chen⁵, Yun Liu⁴, Sifeng Chen¹, Xiaobo Li¹, Ning Sun^{6

7

8}

¹ Department of Physiology and Pathophysiology, State Key Laboratory of Medical Neurobiology, School of Basic Medical Sciences, Fudan University, Shanghai, 200032, China.
² Shanghai Institute of Precision Medicine, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China.
³ Shanghai Key Laboratory of Clinical Geriatric Medicine, Research Center on Aging and Medicine, Fudan University, Shanghai, 200032, China.
⁴ Department of Biochemistry, School of Basic Medical Sciences, Fudan University, Shanghai, 200032, China.
⁵ Department of Echocardiography, Zhongshan Hospital, Fudan University, Shanghai, 200032, China.
⁶ Department of Physiology and Pathophysiology, State Key Laboratory of Medical Neurobiology, School of Basic Medical Sciences, Fudan University, Shanghai, 200032, China. sunning@fudan.edu.cn.
⁷ Shanghai Key Lab of Birth Defect, Children's Hospital of Fudan University, Shanghai, 201102, China. sunning@fudan.edu.cn.
⁸ Shanghai Key Laboratory of Clinical Geriatric Medicine, Research Center on Aging and Medicine, Fudan University, Shanghai, 200032, China. sunning@fudan.edu.cn.

^# Contributed equally.

No abstract available

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