Andexanet Alfa Use for Small Bowel Obstruction Patient With History of Sugiura Procedure

Mil Med. 2021 Jul 1;186(7-8):826-828. doi: 10.1093/milmed/usab151.

Abstract

This case report is about a 51-year-old active duty male with JAK2 mutation and medical history significant for prehepatic portal hypertension from portal vein thrombus on lifelong anticoagulation with rivaroxaban, an oral factor Xa inhibitor, presenting with closed-loop small bowel obstruction requiring emergent laparotomy. We present this surgical case as it required emergent reversal of the oral factor Xa inhibitor with andexanet alfa.

Publication types

  • Case Reports

MeSH terms

  • Blood Coagulation
  • Factor Xa Inhibitors* / pharmacology
  • Factor Xa*
  • Humans
  • Male
  • Middle Aged
  • Recombinant Proteins
  • Rivaroxaban / pharmacology

Substances

  • Factor Xa Inhibitors
  • PRT064445
  • Recombinant Proteins
  • Rivaroxaban
  • Factor Xa