Spermatic Cord Block Series as a Minimally Invasive Therapy for Chronic Scrotal Content Pain

J Urol. 2021 Sep;206(3):725-732. doi: 10.1097/JU.0000000000001777. Epub 2021 Apr 19.

Abstract

Purpose: The primary aim of our study was to evaluate relief of chronic scrotal content pain after a series of spermatic cord blocks with a combination of local anesthetic and a steroid. Secondary aims were to assess factors associated with a positive response and complications.

Materials and methods: We performed a retrospective chart review of patients who underwent spermatic cord block series for chronic scrotal content pain at our practice between 2012 and 2019. Pain scores were compared before and after treatment using an 11-point numerical pain rating scale. We performed univariate analysis to assess differences between responders and nonresponders, and the relationship between symptom duration and response was analyzed by rank-order correlation.

Results: We included 44 men with chronic scrotal content pain present for a median duration of 24 months who underwent a spermatic cord block series. At a median followup of 16 months, 31 patients (70.5%) experienced sustained relief, including 9 patients (20.5%) with complete resolution of pain. There were no differences between responders and nonresponders in terms of symptom duration, perceived etiology, or previous treatments, and there was no association between response and duration of pain. Minor complications occurred in 5 cases (11.4%).

Conclusions: Spermatic cord block series is a safe, minimally invasive treatment for men with refractory chronic scrotal content pain. Response to cord block series appears to be independent of symptom duration, perceived etiology or prior medical and surgical treatments. Future studies should be conducted to evaluate long-term durability and predictors of success.

Keywords: Wallerian degeneration; chronic pain; nerve block; spermatic cord.

MeSH terms

  • Adult
  • Aged
  • Anesthetics, Local / administration & dosage
  • Chronic Pain / diagnosis
  • Chronic Pain / etiology
  • Chronic Pain / therapy*
  • Glucocorticoids / administration & dosage
  • Humans
  • Male
  • Middle Aged
  • Nerve Block / methods*
  • Pain Measurement
  • Retrospective Studies
  • Scrotum / innervation
  • Spermatic Cord / drug effects*
  • Testicular Diseases / complications
  • Testicular Diseases / diagnosis
  • Testicular Diseases / therapy*
  • Treatment Outcome
  • Young Adult

Substances

  • Anesthetics, Local
  • Glucocorticoids