Endocarditis and systemic embolization from Whipple's disease

Yu Ting He; Katherine Peterson; Jessica Crothers; Jean Dejace; Andrew J Hale

doi:10.1016/j.idcr.2021.e01105

Endocarditis and systemic embolization from Whipple's disease

IDCases. 2021 Mar 31:24:e01105. doi: 10.1016/j.idcr.2021.e01105. eCollection 2021.

Authors

Yu Ting He¹, Katherine Peterson¹, Jessica Crothers², Jean Dejace², Andrew J Hale²

Affiliations

¹ University of Vermont Medical Center, Burlington, VT, United States.
² University of Vermont Medical Center, Larner College of Medicine at the University of Vermont, Burlington, VT, United States.

Abstract

Whipple's disease (WD), caused by infection with the organism Tropheryma whipplei, is a rare disease that classically presents with diarrhea, weight loss, and polyarthralgia. Less commonly, Whipple's Disease can presentation with endocarditis or neurologic infections. The authors report a patient with Whipple's Disease endocarditis whose initial presentation was acute lower extremity arterial occlusion, and review current literature regarding the epidemiology, diagnosis, treatment, and prognosis of Whipple's Disease endocarditis.

Keywords: Endocarditis; Tropheryma whipplei; Whipple’s disease.

Publication types

Case Reports