Irreversible Homonymous Hemianopia Associated with Severe Hyperglycemia and Cerebral Hyperperfusion: A Case Report and Literature Review

Intern Med. 2021 Oct 1;60(19):3161-3166. doi: 10.2169/internalmedicine.6994-21. Epub 2021 Apr 19.

Abstract

A 68-year-old man was admitted to our department because of left incomplete homonymous hemianopia accompanied by hyperglycemia. Both T2-weighted and diffusion-weighted imaging revealed a low signal intensity along the subcortex and high signal intensity along the cortex on the right parietal and occipital lobes. Furthermore, arterial spin labeling and single-photon emission computed tomography showed hyperperfusion at the right parieto-occipital lobe. However, the electroencephalography result was normal. Hyperperfusion improved after controlling the blood glucose levels; nevertheless, homonymous hemianopia remained. We suspect that the irreversible brain damage was attributable to hyperperfusion associated with long-term hyperglycemia.

Keywords: epilepsy; homonymous hemianopia; hyperglycemia; hyperperfusion; single-photon emission computed tomography.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Aged
  • Electroencephalography
  • Hemianopsia* / diagnosis
  • Hemianopsia* / etiology
  • Humans
  • Hyperglycemia* / complications
  • Hyperglycemia* / diagnosis
  • Magnetic Resonance Imaging
  • Male
  • Occipital Lobe / diagnostic imaging
  • Tomography, Emission-Computed, Single-Photon