Plant virus-interactions: unraveling novel defense mechanisms under immune-suppressing pressure

Abstract

Plants have developed multilayered molecular defense strategies to combat pathogens. These defense layers have been predominantly identified and characterized in incompatible interactions, in which the plant immune system induces a rapid and efficient defense. Nevertheless, due to the constant evolutionary pressure between plants and pathogens for dominance, it is conceptually accepted that several mechanisms of plant defense may be hidden by the co-evolving immune-suppressing functions from pathogens. Recent studies focusing on begomovirus-host interactions have provided an in-depth view of how suppressed plant antiviral mechanisms can offer a more dynamic view of evolving pressures in the immune system also shared with nonviral pathogens. The emerging theme of crosstalk between host antiviral defenses and antibacterial immunity is also discussed. This interplay between immune responses allows bacteria and viruses to activate immunity against pathogens from a different kingdom, hence preventing multiple infections presumably to avoid competition.