Precision radiogenomics: fusion biopsies to target tumour habitats in vivo

Mireia Crispin-Ortuzar; Evis Sala

doi:10.1038/s41416-021-01381-2

Precision radiogenomics: fusion biopsies to target tumour habitats in vivo

Br J Cancer. 2021 Sep;125(6):778-779. doi: 10.1038/s41416-021-01381-2. Epub 2021 Apr 16.

Authors

Mireia Crispin-Ortuzar^{1

2}, Evis Sala^{3

4}

Affiliations

¹ Cancer Research UK Cambridge Centre, University of Cambridge, Cambridge, UK. mc973@cam.ac.uk.
² Department of Oncology, University of Cambridge, Cambridge, UK. mc973@cam.ac.uk.
³ Cancer Research UK Cambridge Centre, University of Cambridge, Cambridge, UK.
⁴ Department of Radiology, University of Cambridge, Cambridge, UK.

Abstract

High-grade serous ovarian cancer lesions display a high degree of heterogeneity on CT scans. We have recently shown that regions with distinct imaging profiles can be accurately biopsied in vivo using a technique based on the fusion of CT and ultrasound scans.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Cystadenocarcinoma, Serous / diagnosis*
Cystadenocarcinoma, Serous / genetics
Cystadenocarcinoma, Serous / pathology
Female
Genomics / methods*
Humans
Image-Guided Biopsy / methods*
Neoplasm Grading
Ovarian Neoplasms / diagnosis*
Ovarian Neoplasms / genetics
Ovarian Neoplasms / pathology
Precision Medicine
Tomography, X-Ray Computed
Ultrasonography