Multiscale Structural Elucidation of Peptide Nanotubes by X-Ray Scattering Methods

Front Bioeng Biotechnol. 2021 Mar 29:9:654339. doi: 10.3389/fbioe.2021.654339. eCollection 2021.

Abstract

This mini-review presents the structural investigations of the self-assembled peptide nanotubes using X-ray scattering techniques. As compared to electron microscopy, scattering methods enable studies of nanotubes in solution under the appropriate physicochemical conditions and probe their formation mechanism. In addition, a combination of X-ray scattering methods allow the elucidation of structural organization from the molecular scale to the dimension of nanotubes.

Keywords: SAXS; X-ray scattering; peptide nanoribbons; peptide nanotubes; peptide self-assembly.

Publication types

  • Review