The effect of oat bran consumption on gestational diabetes: a randomized controlled clinical trial

BMC Endocr Disord. 2021 Apr 13;21(1):67. doi: 10.1186/s12902-021-00731-8.

Abstract

Background: Gestational diabetes is the most common medical complication in pregnancy, and it has many side effects for the mother and the fetus. The aim of this study was to evaluate the effect of oat bran consumption on gestational diabetes.

Methods: This study is a randomized clinical trial that was performed on 112 women with gestational diabetes treated with diet. Participants were randomly divided into two groups of 56. Participants in both groups were given a diet for gestational diabetes. In addition to the diet, the intervention group received 30 g of oat bran daily for 4 weeks at lunch and dinner. Tests of fasting blood glucose and two-hour postprandial (2hpp) glucose were taken from both groups: before the intervention, and 2 and 4 weeks after the start of the intervention. Data analysis was performed using SPSS statistical software (version 22) using independent t-test, as well as Chi-square and Mann-Whitney tests. P values less than 0.05 were considered statistically significant.

Results: There was no statistically significant difference between the two groups in terms of mean blood glucose before the intervention, while 2 and 4 weeks after the intervention, mean fasting blood glucose and two-hour postprandial (2hpp) glucose decreased significantly in the intervention group compared with the control group (P < 0.001).

Conclusion: Based on the results of this study, the addition of oat bran to the standard diet for pregnant women with gestational diabetes reduced fasting blood glucose and two-hour postprandial (2hpp) glucose. More detailed studies with higher sample sizes are recommended to prove the effectiveness of this valuable dietary supplement.

Trial registration: IRCT registration number: IRCT20191220045828N1 . Registration date: 2020-04-18. Registered while recruiting.

Keywords: Fasting blood sugar; Oat bran; Two-hour post-prandial (2hpp) glucose.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Avena*
  • Blood Glucose / metabolism
  • Diabetes, Gestational / blood*
  • Diabetes, Gestational / diet therapy*
  • Diabetes, Gestational / epidemiology
  • Dietary Fiber / administration & dosage*
  • Female
  • Follow-Up Studies
  • Humans
  • Iran / epidemiology
  • Pregnancy

Substances

  • Blood Glucose
  • Dietary Fiber