Variation in Cannabinoid Metabolites Present in the Urine of Adults Using Medical Cannabis Products in Massachusetts

Jodi M Gilman; William A Schmitt; Grace Wheeler; Randi M Schuster; Jost Klawitter; Cristina Sempio; A Eden Evins

doi:10.1001/jamanetworkopen.2021.5490

Variation in Cannabinoid Metabolites Present in the Urine of Adults Using Medical Cannabis Products in Massachusetts

JAMA Netw Open. 2021 Apr 1;4(4):e215490. doi: 10.1001/jamanetworkopen.2021.5490.

Authors

Jodi M Gilman^{1

2

3}, William A Schmitt¹, Grace Wheeler¹, Randi M Schuster^{1

2}, Jost Klawitter⁴, Cristina Sempio⁴, A Eden Evins^{1

2}

Affiliations

¹ Center for Addiction Medicine, Department of Psychiatry, Massachusetts General Hospital, Boston.
² Harvard Medical School, Boston, Massachusetts.
³ Athinoula A. Martinos Center for Biomedical Imaging, Charlestown, Massachusetts.
⁴ Department of Anesthesiology, University of Colorado, Aurora.

Abstract

This cohort study examines the association between medical cannabis product use and exposure to Δ9-tetrahydrocannabinol and cannabidiol by quantifying levels of their metabolites in urine.

Publication types

Research Support, N.I.H., Extramural

MeSH terms

Adult
Cannabidiol* / administration & dosage
Cannabidiol* / urine
Cannabinoids / administration & dosage
Cannabinoids / urine
Cannabis / chemistry*
Cohort Studies
Dronabinol* / administration & dosage
Dronabinol* / urine
Female
Humans
Male
Marijuana Use*
Massachusetts
Medical Marijuana / chemistry*
Middle Aged

Substances

Cannabinoids
Medical Marijuana
Cannabidiol
Dronabinol

Grants and funding

R01 DA042043/DA/NIDA NIH HHS/United States