Realizing strong photon-photon interactions in a solid-state setting is a major goal with far reaching potential for optoelectronic applications. Using Landau's quasiparticle framework combined with a microscopic many-body theory, we explore the interactions between exciton-polaritons and trions in a two-dimensional semiconductor injected with an electron gas inside a microcavity. We show that particle-hole excitations in the electron gas mediate an attractive interaction between the polaritons, whereas the interaction between trions and polaritons mediated by the exchange of an electron can be either repulsive or attractive. These mediated interactions are intrinsic to the quasiparticles and are also present in the absence of light. Importantly, they can be tuned to be more than an order of magnitude stronger than the direct polariton-polariton interaction in the absence of the electron gas, thereby providing a promising outlook for nonlinear optical components. Finally, we compare our theoretical predictions to two recent experiments.