The novel HLA-DQB1*06:03:27 allele characterised by sequence-based typing in a European bone marrow donor

HLA. 2021 Nov;98(5):498-500. doi: 10.1111/tan.14271. Epub 2021 Apr 14.

Authors

Francisco Boix¹, María Carmen Chillón¹, Sergio García-Sánchez¹, Miguel Alcoceba¹, Luis Alberto Marín-Rubio²

Affiliations

¹ Department of Haematology, University Hospital of Salamanca (HUS-IBSAL), CIBERONC, and Cancer Research Institute of Salamanca-IBMCC (CSIC-USAL University), Salamanca, Spain.
² Department of Clinical Analysis, Immunology Unit, Albacete University Hospital Complex, Albacete, Spain.

PMID: 33834633
DOI: 10.1111/tan.14271

Abstract

A single nucleotide substitution in exon 3 of HLA-DQB1*06:03:01 results in a new allele, HLA-DQB1*06:03:27.

Keywords: HLA-DQB1*06:03:27; NGS; SBT; novel allele.

© 2021 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Alleles
Bone Marrow*
HLA-DQ beta-Chains / genetics
Histocompatibility Testing
Humans

Substances

HLA-DQ beta-Chains
HLA-DQB1 antigen