Prostate cancer testicular metastasis: Are they underestimated? Case report and analysis of the literature

Urologia. 2022 Nov;89(4):645-647. doi: 10.1177/03915603211009118. Epub 2021 Apr 8.

Abstract

Introduction: We aim to present a rare case of a patient who developed a late testicular metastasis of PCa after radical prostatectomy.

Case description: A 78 years old man presenting for left testicular swelling slowly increasing of size over the last 2 months. He underwent a retropubic radical prostatectomy and extended bilateral lymphadenectomy in 2007 for prostatic adenocarcinoma. At the time of the presentation the last PSA was 0.91 ng/mL. The patient underwent a standard left orchifunicolectomy in April 2019 without intra- or perioperative complications. The pathological analysis showed a testicular metastasis of acinar adenocarcinoma.

Conclusions: In conclusion, testicular metastasis from PCa are uncommon conditions. PSA evaluation and physical examination of all sites of metastasis and accurate evaluation of all signs/symptoms during the clinical visit remains crucial to the diagnosis of recurrence.

Keywords: PSA; Prostate cancer; metastasis; orchiectomy; urology.

Publication types

  • Case Reports

MeSH terms

  • Adenocarcinoma* / secondary
  • Adenocarcinoma* / surgery
  • Aged
  • Humans
  • Male
  • Neoplasms, Germ Cell and Embryonal* / surgery
  • Neoplasms, Second Primary* / surgery
  • Prostate-Specific Antigen
  • Prostatectomy
  • Prostatic Neoplasms* / pathology
  • Testicular Neoplasms* / diagnosis

Substances

  • Prostate-Specific Antigen