Infectious Scleritis due to Methicillin-resistant Staphylococcus Aureus after Dengue Viral Fever

Ocul Immunol Inflamm. 2022 Aug;30(6):1544-1546. doi: 10.1080/09273948.2021.1900877. Epub 2021 Apr 8.

Abstract

Purpose: Dengue fever is a severe mosquito-borne disease which can present with various severe ocular manifestations. We aim to report a case of infectious scleritis in dengue fever, occurring due to Methicillin-resistant Staphylococcus aureus (MRSA), managed with intravenous Teicoplanin.

Methods: Case report.

Results: A 23-year-old woman with recent hospitalization for dengue fever presented with severe pain and a nodular scleral lesion. She was initially diagnosed with immune-mediated scleritis, but as the condition worsened, she underwent scleral scraping which subsequently grew MRSA. She was initially started on topical vancomycin eye drops and topical linezolid but there was further worsening. Therapy was switched to intravenous Teicoplanin which resulted in rapid resolution of the condition.

Conclusion: To the best of our knowledge, this is the first reported case of infectious scleritis in association with dengue fever due to MRSA.

Keywords: Dengue fever; Teicoplanin; infectious scleritis; methicillin-resistant staphylococcus aureus; ophthalmic manifestations in dengue fever.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Animals
  • Anti-Bacterial Agents / therapeutic use
  • Dengue* / complications
  • Dengue* / diagnosis
  • Female
  • Humans
  • Methicillin-Resistant Staphylococcus aureus*
  • Scleritis* / diagnosis
  • Scleritis* / drug therapy
  • Scleritis* / etiology
  • Staphylococcal Infections* / complications
  • Staphylococcal Infections* / diagnosis
  • Staphylococcal Infections* / drug therapy
  • Teicoplanin
  • Young Adult

Substances

  • Teicoplanin
  • Anti-Bacterial Agents