Contribution of sleep quality to fatigue following a stroke: a cross-sectional study

BMC Neurol. 2021 Apr 7;21(1):151. doi: 10.1186/s12883-021-02174-z.

Abstract

Background: The prevalence of fatigue and sleep disturbances is high in stroke populations. Sleep quality can be targeted by interventions to alleviate fatigue following a stroke. This study aimed to determine the prevalence of fatigue and poor sleep quality, and to quantify the contribution of sleep quality to fatigue following a stroke, in chronic (≥1 year) stroke survivors.

Methods: A cross-sectional design was adopted. A total of 112 stroke survivors (mean age ± standard deviation [year], 64.18 ± 5.77) at 6.08 ± 4.80 years post-stroke completed this study. All participants were assessed using the Fatigue Assessment Scale, the Pittsburgh Sleep Quality Index, the Visual Analogue Scale-Pain, the Fugl-Meyer Assessment of the upper and lower extremities, the 5-Time Sit-To-Stand Test, the Epworth Sleepiness Scale, the Frenchay Activities Index, the Life-Space Assessment, the Community Integration Measure, and the Multidimensional Scale of Perceived Social Support. Pearson and partial correlation coefficients were used to examine the correlation between fatigue and other variables. A multiple linear regression (the forced entry method) was performed to quantify the independent contribution of sleep quality to prediction of fatigue.

Results: Of the 112 participants, 52.7% reported experiencing fatigue and 64.3% reported poor sleep quality. Sleep quality could independently account for 5.9% of the variance in fatigue scores after a stroke.

Conclusions: There is a high prevalence of fatigue and poor sleep quality in Chinese stroke survivors. Sleep quality is an independent predictor of fatigue in those living in the community who have survived a stroke for a year or longer.

Keywords: Fatigue; Independent living; Regression analysis; Sleep; Stroke.

MeSH terms

  • Aged
  • Cross-Sectional Studies
  • Fatigue / epidemiology*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Prevalence
  • Sleep / physiology
  • Sleep Initiation and Maintenance Disorders / epidemiology
  • Sleep Wake Disorders / epidemiology*
  • Stroke / complications*
  • Survivors