Electroanalysis of Biomolecules: Rational Selection of Sensor Construction

Biochemistry (Mosc). 2021 Jan;86(Suppl 1):S140-S151. doi: 10.1134/S0006297921140108.

Abstract

Methods of electrochemical analysis of biological objects based on the reaction of electro-oxidation/electro-reduction of molecules are presented. Polymer nanocomposite materials that modify electrodes to increase sensitivity of electrochemical events on the surface of electrodes are described. Examples of applications electrochemical biosensors constructed with nanocomposite material for detection of biological molecules are presented, advantages and drawbacks of different applications are discussed.

Keywords: DNA; biosensors; electroanalysis; heme proteins; label-free detection; multi-walled carbon nanotubes.

Publication types

  • Review

MeSH terms

  • Biosensing Techniques*
  • DNA / analysis
  • Electrochemical Techniques / methods*
  • Nanocomposites
  • Nanotubes

Substances

  • DNA