Radiosurgery, reirradiation, and brachytherapy

Pediatr Blood Cancer. 2021 May:68 Suppl 2:e28531. doi: 10.1002/pbc.28531.

Abstract

Radiosurgery and brachytherapy are potentially useful treatment techniques that are sparingly applied in pediatric oncology. They are often used in the setting of reirradiation for recurrent or metastatic tumors. Reirradiation in children with recurrent tumors is complicated by the tolerance of critical organs and the potential risks for overall long-term dose-dependent complications. We review the current literature available in support of reirradiation and the use of radiosurgery and brachytherapy in pediatric patients.

Keywords: brachytherapy; brain tumors; radiosurgery; recurrence; reirradiation; sarcomas; toxicity.

Publication types

  • Review

MeSH terms

  • Brachytherapy / methods*
  • Child
  • Combined Modality Therapy
  • Humans
  • Neoplasms / pathology
  • Neoplasms / therapy*
  • Radiosurgery / methods*
  • Re-Irradiation / methods*