Dramatic Response to Carboplatin Plus Paclitaxel in Pancreatic Mucinous Cystadenocarcinoma with Liver Metastasis

Intern Med. 2021 Sep 15;60(18):2967-2971. doi: 10.2169/internalmedicine.6730-20. Epub 2021 Apr 5.

Abstract

Mucinous cystic neoplasm (MCN) of the pancreas is a rare cystic tumor occurring in the pancreatic body and tail in young to middle-aged women that is pathologically characterized by an ovarian-like stroma. Chemotherapy for recurrent/advanced pancreatic MCN has been based on chemotherapy regimens for pancreatic ductal adenocarcinoma, but the prognosis is poor. We herein report a 37-year-old woman with pancreatic mucinous cystadenocarcinoma with liver metastasis that responded dramatically to carboplatin plus paclitaxel therapy (CBDCA+PTX). CBDCA+PTX may be a treatment option for recurrent/advanced pancreatic MCN with an ovarian-like stroma.

Keywords: carboplatin; mucinous cystadenocarcinoma; paclitaxel; pancreas.

Publication types

  • Case Reports

MeSH terms

  • Adenocarcinoma*
  • Adult
  • Carboplatin
  • Cystadenocarcinoma, Mucinous* / drug therapy
  • Female
  • Humans
  • Liver Neoplasms* / drug therapy
  • Paclitaxel
  • Pancreatic Neoplasms* / drug therapy

Substances

  • Carboplatin
  • Paclitaxel