The Promising Evolution of Targeted Therapeutic Strategies in Cancer

Solange Peters; Tony Mok; Antonio Passaro; Pasi Antero Jänne

doi:10.1158/2159-8290.CD-21-0124

The Promising Evolution of Targeted Therapeutic Strategies in Cancer

Cancer Discov. 2021 Apr;11(4):810-814. doi: 10.1158/2159-8290.CD-21-0124.

Authors

Solange Peters^#¹, Tony Mok^#², Antonio Passaro^#³, Pasi Antero Jänne^#⁴

Affiliations

¹ Department of Oncology, Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland. solange.peters@chuv.ch.
² State Key Laboratory in Translational Oncology, Department of Clinical Oncology, Chinese University of Hong Kong, Hong Kong, P.R. China.
³ Division of Thoracic Oncology, European Institute of Oncology, IRCCS, Milan, Italy.
⁴ Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts.

^# Contributed equally.

PMID: 33811117
DOI: 10.1158/2159-8290.CD-21-0124

Abstract

The upcoming decade of precision medicine for cancer is moving from the translation of specific genetic findings into clinically relevant improvement to the qualitative analyses of the genomic and immune tumor microenvironment, for an integrated treatment strategy in both metastatic and early disease.

MeSH terms

Humans
Neoplasms / therapy*
Precision Medicine / trends*
Tumor Microenvironment