Mitochondrial DNA Profiles of Individuals from a 12th Century Necropolis in Feldioara (Transylvania)

Genes (Basel). 2021 Mar 19;12(3):436. doi: 10.3390/genes12030436.

Abstract

The genetic signature of modern Europeans is the cumulated result of millennia of discrete small-scale exchanges between multiple distinct population groups that performed a repeated cycle of movement, settlement, and interactions with each other. In this study we aimed to highlight one such minute genetic cycle in a sea of genetic interactions by reconstructing part of the genetic story of the migration, settlement, interaction, and legacy of what is today the Transylvanian Saxon. The analysis of the mitochondrial DNA control region of 13 medieval individuals from Feldioara necropolis (Transylvania region, Romania) reveals a genetically heterogeneous group where all identified haplotypes are different. Most of the perceived maternal lineages are of Western Eurasian origin, except for the Central Asiatic haplogroup C seen in only one sample. Comparisons with historical and modern populations describe the contribution of the investigated Saxon settlers to the genetic history of this part of Europe.

Keywords: Transylvania; medieval individuals; mitochondrial DNA; population genetics.

Publication types

  • Historical Article
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Asia / ethnology
  • DNA, Ancient / analysis*
  • DNA, Mitochondrial / genetics
  • DNA, Mitochondrial / history*
  • Genetics, Population
  • History, Medieval
  • Humans
  • Mitochondria / genetics*
  • Phylogeny
  • Population Dynamics
  • Romania / ethnology
  • White People / genetics*

Substances

  • DNA, Ancient
  • DNA, Mitochondrial