Fetal Growth Acceleration-Current Approach to the Big Baby Issue

Medicina (Kaunas). 2021 Mar 2;57(3):228. doi: 10.3390/medicina57030228.

Abstract

Background and Objectives: Fetal overgrowth is related to many perinatal complications, including stillbirth, cesarean section, maternal and neonatal injuries, and shoulder dystocia. It is related to maternal diabetes, obesity, and gestational weight gain but also happens in low-risk pregnancies. There is ongoing discussion regarding definitions, methods of detection, and classification. The method used for detection is crucial as it draws a line between those at risk and low-risk popula-tions. Materials and Methods: For this narrative review, relevant evidence was identified through PubMed search with one of the general terms (macrosomia, large-for-gestational-age) combined with the outcome of interest. Results: This review summarizes evidence on the relation of fetal overgrowth with stillbirth, cesarean sections, shoulder dystocia, anal sphincter injury, and hem-orrhage. Customized growth charts help to detect mothers and fetuses at risk of those complica-tions. Relations between fetal overgrowth and diabetes, maternal weight, and gestational weight gain were investigated. Conclusions: a substantial proportion of complications are an effect of the fetus growing above its potential and should be recognized as a new dangerous condition of Fetal Growth Acceleration.

Keywords: diabetes; diagnostic techniques; fetal growth acceleration; fetal macrosomia; gestational; large-for-gestational-age; obstetrical and gynecological; obstetrics; pregnancy complications; stillbirth.

Publication types

  • Review

MeSH terms

  • Acceleration
  • Cesarean Section
  • Diabetes, Gestational* / epidemiology
  • Dystocia* / epidemiology
  • Female
  • Fetal Macrosomia / epidemiology
  • Humans
  • Infant
  • Infant, Newborn
  • Pregnancy