Recent Advances in the Detection of Antibiotic and Multi-Drug Resistant Salmonella: An Update

Int J Mol Sci. 2021 Mar 28;22(7):3499. doi: 10.3390/ijms22073499.

Abstract

Antibiotic and multi-drug resistant (MDR) Salmonella poses a significant threat to public health due to its ability to colonize animals (cold and warm-blooded) and contaminate freshwater supplies. Monitoring antibiotic resistant Salmonella is traditionally costly, involving the application of phenotypic and genotypic tests over several days. However, with the introduction of cheaper semi-automated devices in the last decade, strain detection and identification times have significantly fallen. This, in turn, has led to efficiently regulated food production systems and further reductions in food safety hazards. This review highlights current and emerging technologies used in the detection of antibiotic resistant and MDR Salmonella.

Keywords: Salmonella; detection; genotypic; multi-drug resistant; phenotypic.

Publication types

  • Review

MeSH terms

  • Animals
  • Anti-Bacterial Agents / pharmacology
  • Antimicrobial Stewardship
  • Biosensing Techniques
  • Drug Resistance, Multiple, Bacterial*
  • Food Microbiology
  • Food Safety
  • Genotype
  • Humans
  • Microbial Sensitivity Tests*
  • Multigene Family
  • Pharmaceutical Preparations
  • Phenotype
  • Polymerase Chain Reaction
  • Salmonella / drug effects*
  • Salmonella Infections / drug therapy*
  • Salmonella Infections / microbiology
  • Spectrum Analysis, Raman
  • Whole Genome Sequencing

Substances

  • Anti-Bacterial Agents
  • Pharmaceutical Preparations