Exhaled breath biomarker sensing

Biosens Bioelectron. 2021 Jun 15:182:113193. doi: 10.1016/j.bios.2021.113193. Epub 2021 Mar 26.

Abstract

This goal of this minireview is to introduce the reader to the area of research concerned with exhaled breath analysis for the purpose of detecting abnormal levels of physiologically-relevant chemical markers reflective of respiratory diseases. Two main two groups of sensing methods are reviewed: mass spectrometry and (bio)sensors. The discussion focuses on biosensor applications for EB and EBC analyses, which are presented in detail. The review finishes with conclusions and future perspectives, including recommendations for future near-term and long-term development of EBC biomarker sensing.

Keywords: Biomarkers; Biosensors; Chemical sensors; Exhaled breath condensate.

MeSH terms

  • Biomarkers
  • Biosensing Techniques*
  • Body Fluids*
  • Breath Tests
  • Exhalation

Substances

  • Biomarkers