Inheriting the medicinal illustrations in Bencao Tujing(, Illustration of Materia Medica), the two picture books of Zhenghe Bencao(, Pharmacopoeia of the Zhenghe reign) Huiming Sanctum edition and Daguan Bencao(, Pharmacopoeia of the Daguan reign) Liu Jia edition show different styles and characteristics in illustrations. They present different art styles and features in medicinal illustrations of ores, plants and animals because of the regional influences from the south and the north. In the process of carving and printing the illustrations of the two classics, different attitudes lead to similarities in the outline and yet differences in details. Besides, the different artistic levels in carving and printing contribute to different artistic standards. Compared with the paintings created in Song Dynasty, more subtle features are lost in Zhenghe Bencao(Huiming Sanctum edition) than in Daguan Bencao (Liu Jia edition). Therefore, the Zhenglei Bencao (, Collected Classified Materia Medica) Huiming Sanctum edition are much closer to the ones in Bencao Tujing and the real medicinals as well than those in Daguan Bencao (Liu Jia edition).
晦明轩本《政和本草》与刘甲本《大观本草》的药图在继承《本草图经》药图的基础上，展现出不同的风格和特点。通过对2个版本《证类本草》中矿石、植物、动物三大类药部图谱进行比较发现，二者在南北殊域的影响下，展现出不同的艺术风格和特色；刊刻者秉持的不同刊刻态度，呈现出外轮廓形似而具体细节存在差异的特点；在刻工艺术水平的影响下，呈现出不同的艺术水准；在宋代绘画的互证下，药物图谱的绘制展现出不同的写实精神。刘甲本《大观本草》与晦明轩本《证类本草》相比较丢失了很多细微特征，因此晦明轩本《证类本草》的图谱相对于刘甲本《大观本草》而言更接近于《本草图经》绘图原貌或者说更接近于现实生活中的真实药物。.