Prevalence of Diabetes in Tuberculosis Patients in Kathmandu Valley, Nepal

Jpn J Infect Dis. 2021 Nov 22;74(6):507-510. doi: 10.7883/yoken.JJID.2019.375. Epub 2021 Mar 31.

Abstract

In this descriptive cross-sectional study, the data on the prevalence of diabetes mellitus (DM) among tuberculosis (TB) patients at the Urban Directly Observed Treatment Centers in the Kathmandu, Bhaktapur, and Lalitpur districts of Nepal were collected. The prevalence of DM was assessed in 67 previously treated TB (PTTB) and 214 new TB patients. DM was diagnosed in 8 PTTB and 20 new TB patients. Clinical interviews identified 14 patients with DM, rapid blood glucose test was used to diagnose DM in 4 patients, and oral glucose tolerance test was used to diagnose DM in another 4 patients. Impaired glucose tolerance and impaired fasting glycemia were observed in 8 and 5 patients, respectively. The 18-24-year age group had the largest number of new TB patients (82, 38.3%). However, the incidence of DM among TB patients was higher in the >35-year age group. Moreover, DM was diagnosed in 24.2% of PTTB patients and in 23.1% of new TB patients. To determine the impact of DM screening in TB patients, a larger number of samples should be analyzed. DM screening for patients with TB is expected to start in developing countries. This should be initiated by conducting clinical interviews about DM and glucose tests using rapid kits.

Keywords: diabetes screening; high risk groups of diabetes mellitus; non-communicable diseases; the End TB strategy; the Sustainable Development Goals.

MeSH terms

  • Adolescent
  • Adult
  • Blood Glucose / analysis*
  • Cross-Sectional Studies
  • Diabetes Mellitus / diagnosis
  • Diabetes Mellitus / epidemiology*
  • Female
  • Glycated Hemoglobin
  • Humans
  • Male
  • Middle Aged
  • Nepal / epidemiology
  • Prevalence
  • Tuberculosis / complications*
  • Tuberculosis / diagnosis
  • Tuberculosis / epidemiology

Substances

  • Blood Glucose
  • Glycated Hemoglobin A