BCL2L2 loss renders -14q renal cancer dependent on BCL2L1 that mediates resistance to tyrosine kinase inhibitors

Clin Transl Med. 2021 Mar;11(3):e348. doi: 10.1002/ctm2.348.

Authors

Yinfeng Lyu^{1

2}, Kunping Li^{1

2}, Yuqing Li^{1

2}, Hui Wen^{1

2}, Chenchen Feng^{1

2}

Affiliations

¹ Department of Urology, Huashan Hospital, Fudan University, Shanghai, P. R. China.
² Institute of Urology, Fudan University, Shanghai, P. R. China.

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Apoptosis Regulatory Proteins / genetics*
Carcinoma, Renal Cell / drug therapy*
Carcinoma, Renal Cell / genetics*
Humans
Kidney Neoplasms / drug therapy*
Kidney Neoplasms / genetics*
Protein Kinase Inhibitors / therapeutic use*
bcl-X Protein / genetics*

Substances

Apoptosis Regulatory Proteins
BCL2L1 protein, human
BCL2L2 protein, human
Protein Kinase Inhibitors
bcl-X Protein