Background: The aim of this study was to investigate the seroprevalence of cytomegalovirus (CMV) infection using the serologic status of CMV IgG and IgM antibodies in Korean women of childbearing age.
Methods: We retrospectively reviewed CMV IgG and IgM test results from Korean women aged 15-49 years who underwent testing between January 2009 and December 2019. Seroprevalence of CMV IgG and IgM by year and age was investigated.
Results: The study period was 11 years, and among 6837 samples tested, 95.8% were CMV IgG-positive. The seropositivity in women aged 15- <20 years was significantly lower (77.5%) than older age groups. Among 6837 total CMV IgG tests, 75.9% (5186) had concurrently measured CMV IgM results among which 2.4% were IgM-positive.
Conclusion: Considering the low CMV seropositivity of women younger than 20 years, they may need prenatal education for CMV infection.
Keywords: congenital infection; cytomegalovirus; maternal screening; seroprevalence.
© 2021 The Authors. Journal of Clinical Laboratory Analysis published by Wiley Periodicals LLC.