Silicone-induced lymphadenopathy mimicking recurrence of breast cancer on positron emission tomography-computed tomography, correctly diagnosed on ultrasound

J Clin Ultrasound. 2021 Jul;49(6):610-613. doi: 10.1002/jcu.23010. Epub 2021 Mar 29.

Abstract

Silicone-induced lymphadenopathy is a rare complication associated with silicone breast implants. It is usually asymptomatic and found incidentally during imaging. We report a case of silicone lymphadenopathy in a patient who had undergone a mastectomy and breast reconstruction for breast cancer. During follow-up, a positron emission tomography-computed tomography examination revealed lymph nodes that were suspicious for cancer recurrence. However, sonography was able to correctly diagnose silicone-induced lymphadenopathy and exclude cancer metastasis.

Keywords: breast cancer; breast implants; internal mammary chains; lymphadenopathy; positron emission tomography; silicone-induced granuloma; snowstorm artifact; ultrasound.

Publication types

  • Case Reports

MeSH terms

  • Breast Implants / adverse effects
  • Breast Neoplasms / diagnosis*
  • Diagnosis, Differential
  • Humans
  • Lymphadenopathy / chemically induced*
  • Lymphadenopathy / diagnostic imaging*
  • Lymphadenopathy / pathology
  • Middle Aged
  • Positron Emission Tomography Computed Tomography*
  • Recurrence
  • Silicones / adverse effects*
  • Ultrasonography

Substances

  • Silicones