Silica Nanoparticles

Hyejin Chang; Jaehi Kim; Won-Yeop Rho; Xuan-Hung Pham; Jong Hun Lee; Sang Hun Lee; Dae Hong Jeong; Bong-Hyun Jun

doi:10.1007/978-981-33-6158-4_3

Silica Nanoparticles

Adv Exp Med Biol. 2021:1309:41-65. doi: 10.1007/978-981-33-6158-4_3.

Authors

Hyejin Chang^#¹, Jaehi Kim^#², Won-Yeop Rho³, Xuan-Hung Pham², Jong Hun Lee⁴, Sang Hun Lee⁵, Dae Hong Jeong⁶, Bong-Hyun Jun⁷

Affiliations

¹ Division of Science Education, Kangwon National University, Chuncheon, Republic of Korea.
² Department of Bioscience and Biotechnology, Konkuk University, Seoul, South Korea.
³ School of International Engineering and Science, Jeonbuk National University, Jeonju, Republic of Korea.
⁴ Department of Food Science and Biotechnology, Gachon University, Seongnam, Republic of Korea.
⁵ Department of Chemical and Biological Engineering, Hanbat National University, Daejeon, Republic of Korea.
⁶ Department of Chemistry Education, Seoul National University, Seoul, Republic of Korea.
⁷ Department of Bioscience and Biotechnology, Konkuk University, Seoul, South Korea. bjun@konkuk.ac.kr.

^# Contributed equally.

PMID: 33782868
DOI: 10.1007/978-981-33-6158-4_3

Abstract

Silica consists of one silicon atom and two oxygen atoms (SiO₂) and is commonly used in various aspects of daily life. For example, it has been used as glass, insulator, and so on. Nowadays, silica is used as core reagents for fabricating and encapsulating nanoparticles (NPs). In this chapter, the usage of silica in nanotechnology is described. Synthesis and surface modification of silica nanoparticles (SiNPs), including via the Stöber method, reverse microemulsion method, and modified sol-gel method, are illustrated. Then, various NPs with silica encapsulation are explained. At last, the biological applications of those mentioned NPs are described.

Keywords: Reverse microemulsion method; Silica nanoparticles; Sol-gel method; Stöber method.

MeSH terms

Nanoparticles*
Nanotechnology
Silicon Dioxide*

Substances

Silicon Dioxide