18F-PSMA-1007 Uptake in Pulmonary Lymphangitic Carcinomatosis Metastasis From Prostate Cancer

Clin Nucl Med. 2021 Jul 1;46(7):e355-e357. doi: 10.1097/RLU.0000000000003582.

Abstract

A 55-year-old man with cough, bone pain, and cervical lymphadenopathy underwent both 18F-FDG and 18F-PSMA-1007 PET/CT scans with clinical suspicion of malignant disease. Compared with 18F-FDG PET/CT, 18F-PSMA PET/CT showed intense tracer uptake in the prostate gland, lungs, osteogenic lesions, and multiple lymph nodes. Interestingly, we also found the high tracer concentration of pulmonary lymphangitic carcinomatosis, a very rare form of prostate cancer metastasis to the lung, on 18F-PSMA-1007 PET/CT images.

Publication types

  • Case Reports

MeSH terms

  • Biological Transport
  • Humans
  • Lung Neoplasms / diagnostic imaging
  • Lung Neoplasms / metabolism*
  • Lung Neoplasms / secondary*
  • Male
  • Middle Aged
  • Niacinamide / analogs & derivatives*
  • Niacinamide / metabolism
  • Oligopeptides / metabolism*
  • Positron Emission Tomography Computed Tomography
  • Prostatic Neoplasms / pathology*

Substances

  • Oligopeptides
  • PSMA-1007
  • Niacinamide