Plant oils: From chemical composition to encapsulated form use

Int J Pharm. 2021 May 15:601:120538. doi: 10.1016/j.ijpharm.2021.120538. Epub 2021 Mar 27.

Abstract

The last decade has witnessed a burgeoning global movement towards essential and vegetable oils in the food, agriculture, pharmaceutical, cosmetic, and textile industries thanks to their natural and safe status, broad acceptance by consumers, and versatile functional properties. However, efforts to develop new therapy or functional agents based on plant oils have met with challenges of limited stability and/or reduced efficacy. As a result, there has been increased research interest in the encapsulation of plant oils, whereby the nanocarriers serve as barrier between plant oils and the environment and control oil release leading to improved efficacy, reduced toxicity and enhanced patient compliance and convenience. In this review, special concern has been addressed to the encapsulation of essential and vegetable oils in three types of nanocarriers: polymeric nanoparticles, liposomes and solid lipid nanoparticles. First, the chemical composition of essential and vegetable oils was handled. Moreover, we gather together the research findings reported by the literature regarding the different techniques used to generate these nanocarriers with their significant findings. Finally, differences and similarities between these nanocarriers are discussed, along with current and future applications that are warranted by their structures and properties.

Keywords: Encapsulation; Essential oil; Liposome; Polymeric nanoparticle; Solid lipid nanoparticle; Vegetable oil.

Publication types

  • Review

MeSH terms

  • Humans
  • Lipids
  • Liposomes
  • Nanoparticles*
  • Oils, Volatile*
  • Plant Oils
  • Polymers

Substances

  • Lipids
  • Liposomes
  • Oils, Volatile
  • Plant Oils
  • Polymers