Long-term cardio-metabolic effects after gestational diabetes: a review

J Matern Fetal Neonatal Med. 2022 Dec;35(25):6021-6028. doi: 10.1080/14767058.2021.1903863. Epub 2021 Mar 28.

Abstract

Women with GDM are at high risk of metabolic syndrome and type 2 diabetes (T2DM). A relationship with GDM and future development of cardiovascular disease (CVD) has been also recognized. Pregnancy and postpartum period in women with GDM give us the opportunity to identify the underlying, often unrecognized, CVD risk factors. Ideally, the postpartum follow-up of this women should be done by a multidisciplinary team to evaluate their cardio-metabolic risk and to counseling regarding lifestyle modification (healthy diet and regular physical activity) and breastfeeding that can reduce their risk. Longer follow-up of these women should be individualized, focusing attention on women at medium-high cardio-metabolic risk. The link between GDM and T2DM-CVD offers us a great opportunity for the diseases prevention.

Keywords: Gestational diabetes mellitus; cardiovascular disease; healthy-lifestyle; post-partum follow up; type 2 diabetes.

Publication types

  • Review

MeSH terms

  • Cardiovascular Diseases* / complications
  • Cardiovascular Diseases* / prevention & control
  • Diabetes Mellitus, Type 2* / etiology
  • Diabetes Mellitus, Type 2* / prevention & control
  • Diabetes, Gestational* / prevention & control
  • Female
  • Humans
  • Life Style
  • Postpartum Period
  • Pregnancy