Current concepts in the prevention, diagnosis and treatment of fracture-related infection (FRI)

Eur J Orthop Surg Traumatol. 2021 Jul;31(5):957-966. doi: 10.1007/s00590-021-02956-8. Epub 2021 Mar 29.

Abstract

Fracture-related infection (FRI) is one of the most challenging complications following operative management of fractures. It can have profound implications for the patient, can be associated with considerable morbidity and often lead to impaired outcomes. There are significant healthcare-related costs. In recent years, there has been significant progress towards developing preventative strategies. Furthermore, diagnostic algorithms and management protocols have recently been reported. Lack of a strong evidence base has previously hindered efforts to implement these and develop established standards of care. There are multiple aspects of care that need to be considered and a multi-disciplinary approach is recommended. In this narrative review, we present the most up-to-date recommendations in the prevention, diagnosis and management of FRI.

Keywords: Fracture; Infection; Osteomyelitis.

Publication types

  • Review

MeSH terms

  • Fractures, Bone*
  • Humans
  • Surgical Wound Infection* / diagnosis
  • Surgical Wound Infection* / prevention & control