Magnetic Resonance Imaging of Orbital Solitary Fibrous Tumors: Radiological-Pathological Correlation Analysis

Ryuhei Masuno; Daisuke Yunaiyama; Yukiko Shishido-Hara; Daisuke Yoshimaru; Chifumi Maruyama; Yoichi Araki; Hiroshi Goto; Toshitaka Nagao; Kazuhiro Saito

doi:10.5334/jbsr.2097

Magnetic Resonance Imaging of Orbital Solitary Fibrous Tumors: Radiological-Pathological Correlation Analysis

J Belg Soc Radiol. 2021 Mar 16;105(1):14. doi: 10.5334/jbsr.2097.

Authors

Ryuhei Masuno¹, Daisuke Yunaiyama¹, Yukiko Shishido-Hara¹, Daisuke Yoshimaru¹, Chifumi Maruyama¹, Yoichi Araki¹, Hiroshi Goto¹, Toshitaka Nagao¹, Kazuhiro Saito¹

Affiliation

¹ Tokyo Medical University, JP.

Abstract

Background: Solitary fibrous tumors (SFTs) are rare and can be misdiagnosed because of their various radiological appearances.

Purpose: To clarify the characteristic MRI findings of SFTs by analyzing their radiological-pathological correlation.

Material and methods: Nine consecutive patients with SFT who underwent magnetic resonance imaging (MRI) prior to surgery were analyzed. Eight patients underwent contrast-enhanced MRI, and three underwent dynamic MRI. Radiological-pathological correlation analysis, co-occurrence matrix, run-length matrix, and histogram analysis were performed to assess the relationship between pathological findings T1- and T2-weighted images (T1-WI and T2-WI).

Results: All nine lesions ranged in size from 20 to 36 mm. Seven lesions were located in the superior portion of the retrobulbar space found outside of the muscle cone, and two lesions in the inferior portion were located within it. No significant correlation was observed between the amount of collagenous tissue and the qualitative evaluation of the signal on T1-WI and T2-WI. Kurtosis on T2-WI was significantly correlated with the amount of collagenous tissue (ρ = -0.97, p < 0.0001) and endothelial cells (ρ = -0.49, p = 0.0479).

Conclusion: Kurtosis in the histogram analysis on T2WI showed a strong correlation with the amount of collagenous tissue.

Keywords: MRI; orbit; solitary fibrous tumor; texture analysis.