Natural Selection of ATP2B1 Underlies Susceptibility to Essential Hypertension

Front Genet. 2021 Mar 11:12:628516. doi: 10.3389/fgene.2021.628516. eCollection 2021.

Lin-Dan Ji^{1

2}, Zhi-Feng Xu³, Nelson L S Tang^{4

5}, Jin Xu^{2

6}

¹ Department of Biochemistry, School of Medicine, Ningbo University, Ningbo, China.
² Zhejiang Key Laboratory of Pathophysiology, School of Medicine, Ningbo University, Ningbo, China.
³ Department of Cardiology, Ningbo No. 7 Hospital, Ningbo, China.
⁴ Department of Chemical Pathology, Faculty of Medicine, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong, China.
⁵ KIZ-CUHK Joint Laboratory of Bio-resources and Molecular Research of Common Diseases, The Chinese University of Hong Kong, Hong Kong, China.
⁶ Department of Preventive Medicine, School of Medicine, Ningbo University, Ningbo, China.

No abstract available

Keywords: ATP2B1; essential hypertension; genome-wide association study; natural selection; single nucleotide polymorphism.