Host-virus interactions mediated by long non-coding RNAs

Ashish Prasad; Manoj Prasad

doi:10.1016/j.virusres.2021.198402

Host-virus interactions mediated by long non-coding RNAs

Virus Res. 2021 Jun:298:198402. doi: 10.1016/j.virusres.2021.198402. Epub 2021 Mar 23.

Authors

Ashish Prasad¹, Manoj Prasad²

Affiliations

¹ National Institute of Plant Genourrent overview ome Research, Aruna Asaf Ali Marg, New Delhi, 110067, India.
² National Institute of Plant Genourrent overview ome Research, Aruna Asaf Ali Marg, New Delhi, 110067, India. Electronic address: manoj_prasad@nipgr.ac.in.

PMID: 33771610
DOI: 10.1016/j.virusres.2021.198402

Abstract

Viruses are obligate pathogens that cause a wide range of diseases across all kingdoms of life. They have a colossal impact on the economy and healthcare infrastructure world-wide. Plants and animals have developed sophisticated molecular mechanisms to defend themselves against viruses and viruses in turn hijack host mechanisms to ensure their survival inside their hosts. Long non-coding (lnc) RNAs have emerged as important macromolecules that regulate plant-virus and animal-virus interactions. Both pro-viral and anti-viral lncRNAs have been reported and they show immense potential to be used as markers and in therapeutics. The current review is focussed on the recent developments that have been made in viral interactions of animals and plants.

Keywords: LincRNA; LncRNA; Sub-viral RNAs; Viroids; Virus; sgRNAs.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Animals
Host Microbial Interactions
Host-Pathogen Interactions
Plant Viruses*
Plants
RNA, Long Noncoding* / genetics

Substances

RNA, Long Noncoding