Sars-Cov-2 infection related inflammatory and demyelinating disease; a brief case series

Mult Scler Relat Disord. 2021 Jun:51:102900. doi: 10.1016/j.msard.2021.102900. Epub 2021 Mar 13.

Abstract

Background: Since March 2020, during the Coronavirus disease 2019 (COVID-19) pandemic, it has been observed that the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has neurological involvement with various clinical tables.

Methods: We present 3 new cases admitted to our clinic with various neurological findings which were affected by SARS-CoV-2.

Results: Imaging studies have shown that inflammatory/demyelinizing lesions appeared in different areas of the central nervous system which were accepted as an atypical demyelinating spectrum associated with Covid 19.

Conclusions: With increasing experience, it has been suggested that SARS-CoV-2 may also have a neurotrophic effect. The spectrum of neurological involvement is also expanding as the pandemic continues. These 3 cases suggest that the virus plays a role in the clinical onset of the inflammatory/demyelinating disease.

Keywords: COVID-19; Demyelinating disease; Neurological involvement.

MeSH terms

  • COVID-19*
  • Central Nervous System
  • Demyelinating Diseases* / complications
  • Demyelinating Diseases* / diagnostic imaging
  • Humans
  • Pandemics
  • SARS-CoV-2