Dual fungal infection with Lomentospora prolificans and Aspergillus fumigatus: A pathogenetic diagnosis elucidated after two decades by sequential examinations

Yoshitsugu Sugiura; Naoshi Sugimoto; Takayuki Takahashi; Tadahiko Matsumoto

doi:10.1002/ccr3.3775

Dual fungal infection with Lomentospora prolificans and Aspergillus fumigatus: A pathogenetic diagnosis elucidated after two decades by sequential examinations

Clin Case Rep. 2021 Jan 18;9(3):1383-1386. doi: 10.1002/ccr3.3775. eCollection 2021 Mar.

Authors

Yoshitsugu Sugiura^{1

2}, Naoshi Sugimoto^{3

4}, Takayuki Takahashi^{4

5}, Tadahiko Matsumoto^{6

7}

Affiliations

¹ Azabu University Sagamihara Japan.
² Department of Parasites Kobe Institute of Health Kobe Japan.
³ Department of Clinical Application Center for iPS Cell Research and Application Kyoto University Kyoto Japan.
⁴ Department of Hematology and Clinical Immunology Kobe City General Hospital Kobe Japan.
⁵ Department of Hematology and Oncology Akasaka Clinic Kobe Japan.
⁶ Ochanomizu Institute for Medical Mycology and Allergology Tokyo Japan.
⁷ Noguchi Dermatology Clinic Kumamoto Japan.

Abstract

A 44-year-old male Japanese was admitted for further post-remission treatments for acute myeloid leukemia. He developed a right orbital abscess. An isolate of Lomentospora prolificans was obtained from the lesion, and orbital biopsy also revealed the presence of Aspergillus fumigatus. This fatal case involved a concurrent dual fungal infection.

Keywords: Aspergillus fumigatus; Lomentospora prolificans; acute myeloid leukemia; aspergillosis; orbital abscess; phaeohyphomycosis.

Publication types

Case Reports