Prevalence of tick-borne haemoparasites and their perceived co-occurrences with viral outbreaks of FMD and LSD and their associated factors

Osama Abas; Amir Abd-Elrahman; Asmaa Saleh; Mohamed Bessat

doi:10.1016/j.heliyon.2021.e06479

Prevalence of tick-borne haemoparasites and their perceived co-occurrences with viral outbreaks of FMD and LSD and their associated factors

Heliyon. 2021 Mar 16;7(3):e06479. doi: 10.1016/j.heliyon.2021.e06479. eCollection 2021 Mar.

Authors

Osama Abas¹, Amir Abd-Elrahman¹, Asmaa Saleh², Mohamed Bessat³

Affiliations

¹ Department of Animal Medicine, Faculty of Veterinary Medicine, Alexandria University, Abbis10, P.O. Box 21917, Egypt.
² Department of Animal Medicine, Faculty of Veterinary Medicine, Damanhur University, Egypt.
³ Department of Parasitology, Faculty of Veterinary Medicine, Alexandria University, Abbis10, P.O. Box 21917, Egypt.

Abstract

Species of Theileria, Babesia, and Anaplasma are Tick-borne pathogens (TBPs) that are prevalent throughout the world, particularly in the tropical and subtropical regions. Associated diseases of Theileriosis, Babesiosis, and Anaplasmosis, respectively, represents a major threat to livestock production in many countries. TBPs have a high prevalence in different geographical locations in Egypt. Foot and mouth disease (FMD) and Lumpy skin disease (LSD) are considered endemic bovine viral diseases in Egypt. Our clinical observations during the epidemics of LSD and FMD viruses showed higher prevalence rates for the TBPs. To investigate this correlation, a total of 670 samples from cattle and buffalo were collected during the summers of 2017 and 2018 distributed throughout ranches and smallholders in two geographical locations in Egypt. Two farms with a recent clinical outbreak of LSD with a total of 270 animals, while the other location included three farms with a recent FMD outbreak with a combined 400 cattle. Examined animals were classified mainly according to age, gender, species, breed (native versus crossbred), and the presence of ticks. Whole blood samples were collected for TBPs and viral (LSD and FMD) examinations, while tissue specimens were collected for detection of FMD and LSD viruses by real-time PCR. Our results confirmed significantly higher prevalence rates for the TBPs in LSD-positive than LSD-negative animals, while no significant difference could be detected for the prevalence rate of the TBPs in the FMD positive and negative groups. The prevalence of Babesia and Theileria was significantly (P < 0.05) higher in cross-breeds than native cattle. Infections with Anaplasma and co-infections with Babesia-Anaplasma and Theileria-Anaplasma were significantly higher in native than cross-breeds cattle. The intensity of parasitic infection (parasitemia) has a significant difference in the positive groups for the two viruses compared to the negative groups. These results collectively confirming the enhancing role of LSD on the prevalence rate of the haemoprotozoal infections leading to more serious outcomes to the livestock infections, and therefore the control of haemoprotozoal infections should be implemented as a part of viral epidemics control.

Keywords: Anaplasma; Babesia; Egypt; Foot and mouth disease; Lumpy skin disease; Theileria; Tick-borne pathogens.