Indicators of antioxidant protection of blood in necrotizing ulcerative gingivitis in experimental animals

Abstract

This article highlights the results of a study of blood parameters in animals with simulated necrotizing ulcerative gingivitis and compares them, under the same conditions, with animals that received local treatment with a developed complex of antioxidant drugs. Following the work tasks, the nature of changes in the state of the antioxidant - prooxidant system and their influence on quantitative and functional indicators of markers of inflammatory intensity was analyzed and investigated during the pathological process in the background and without treatment with a developed complex. This work shows the changes of malonic dialdehyde concentration as an indicator of lipid peroxidation intensity in experimental animals, the level of catalase activity in the blood of animals, and antioxidant-prooxidant balance in the dynamics of necrotizing ulcerative gingivitis.

Keywords: API; API – Antioxidant-Prooxidant Index; CA; CA – Catalase; LPO; LPO – Lipid Peroxidation; MDA; MDA – Malonic Dialdehyde; antioxidants; experimental animals; free radicals; periodontitis; simulated necrotizing ulcerative gingivitis.