Biochemistry and hematology reference intervals for neonatal dairy calves aged 5-12 days

Vet Clin Pathol. 2021 Jun;50(2):278-286. doi: 10.1111/vcp.12955. Epub 2021 Mar 23.

Abstract

Background: Comprehensive hematology and biochemistry RIs are currently lacking in the literature for young dairy calves based on sample sizes more than 120. Young dairy calves are at a relatively high risk of poor health and welfare outcomes. They have a high risk of morbidity and mortality in the first 2 weeks of life, and many are transported and fasted during this time. For example, non-replacement calves in Australia and New Zealand are usually 5-12 days old when transported to abattoirs, meaning that calves of this age group are potentially at risk of both health and welfare compromise. Given these factors, sound, comprehensive, age-specific biochemical and hematologic RIs are needed for both veterinary clinical practice and to inform research on calf health and welfare.

Objectives: The aim of this study was to generate age-specific hematology and biochemistry RIs for dairy calves aged 5-12 days.

Methods: We collected blood samples from 141 fasted, healthy dairy calves on 10 Australian farms. Reference Value Advisor software was used to calculate nonparametric RIs for multiple biochemistry and hematology variables.

Results: RIs for a panel of hematology and biochemistry variables in dairy calves aged 5-12 days old were derived.

Conclusions: These RIs will be useful for clinical veterinary practice, as well as for research on dairy calf health and welfare.

Keywords: Reference Value Advisor; blood; heifer; non-replacement calf; plasma; serum.

MeSH terms

  • Animals
  • Animals, Newborn
  • Australia
  • Cattle
  • Cattle Diseases*
  • Dairying
  • Hematology*
  • New Zealand
  • Reference Values