Cardiovascular and Cerebrovascular Complications With COVID-19

Cardiol Rev. 2021 May-Jun;29(3):143-149. doi: 10.1097/CRD.0000000000000385.

Abstract

The coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus-2 has affected the health of people across the globe. Cardiovascular diseases (CVDs) have a significant relationship with COVID-19, both as a risk factor and prognostic indicator, and as a complication of the disease itself. In addition to predisposing to CVD complications, the ongoing pandemic has severely affected the delivery of timely and appropriate care for cardiovascular conditions resulting in increased mortality. The etiology behind the cardiac injury associated with severe acute respiratory syndrome coronavirus-2 is likely varied, including coronary artery disease, microvascular thrombosis, myocarditis, and stress cardiomyopathy. Further large-scale investigations are needed to better determine the underlying mechanism of myocardial infarction and other cardiac injury in COVID-19 patients and to determine the incidence of each type of cardiac injury in this patient population. Telemedicine and remote monitoring technologies can play an important role in optimizing outcomes in patients with established CVD. In this article, we summarize the various impacts that COVID-19 has on the cardiovascular system, including myocardial infarction, myocarditis, stress cardiomyopathy, thrombosis, and stroke.

Publication types

  • Review

MeSH terms

  • COVID-19 / complications
  • COVID-19 / epidemiology
  • COVID-19 / physiopathology*
  • Cardiovascular Diseases / epidemiology
  • Cardiovascular Diseases / etiology
  • Cardiovascular Diseases / physiopathology*
  • Comorbidity
  • Coronary Artery Disease / epidemiology
  • Coronary Artery Disease / etiology
  • Coronary Artery Disease / physiopathology
  • Coronary Thrombosis / etiology
  • Coronary Thrombosis / physiopathology
  • Heart Disease Risk Factors
  • Humans
  • Ischemic Stroke / epidemiology
  • Ischemic Stroke / etiology
  • Ischemic Stroke / physiopathology
  • Microvessels
  • Myocardial Infarction / epidemiology
  • Myocardial Infarction / etiology
  • Myocardial Infarction / physiopathology
  • Myocarditis / etiology
  • Myocarditis / physiopathology
  • SARS-CoV-2
  • Stroke / epidemiology
  • Stroke / etiology
  • Stroke / physiopathology
  • Takotsubo Cardiomyopathy / etiology
  • Takotsubo Cardiomyopathy / physiopathology
  • Thrombosis / etiology
  • Thrombosis / physiopathology