Improving Treatment and Outcomes for Melioidosis in Children, Northern Cambodia, 2009-2018

Emerg Infect Dis. 2021 Apr;27(4):1169-1172. doi: 10.3201/eid2704.201683.

Abstract

We report trends in manifestations, treatment, and outcomes of 355 children with culture-confirmed melioidosis over 10 years at a pediatric hospital in northern Cambodia. Bacteremia and presentation with pneumonia were risk factors for death. A total of 39 children recovered after being given only oral antimicrobial drug treatment.

Keywords: Burkholderia pseudomallei; Cambodia; amoxicillin/clavulanic acid; bacteria; children; melioidosis; outcomes; pediatrics; treatment; trimethoprim/sulfamethoxazole.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Bacterial Agents / therapeutic use
  • Burkholderia pseudomallei*
  • Cambodia
  • Child
  • Humans
  • Melioidosis* / drug therapy
  • Treatment Outcome

Substances

  • Anti-Bacterial Agents