During the 2019 Eastern equine encephalitis virus (EEEV) outbreak in Michigan, two 2-month old Mexican wolf pups experienced neurologic signs, lymphohistiocytic neutrophilic meningoencephalitis with neuronal necrosis and neuronophagia, and acute death. We identified EEEV by reverse transcription real-time PCR and in situ hybridization. Vector mosquitoes were trapped at the zoo.
Keywords: Eastern equine encephalitis virus; Michigan; United States; meningitis/encephalitis; meningoencephalitis; mosquitoes; vector-borne infections; viruses; wolf.