Acute Kidney Disease to Chronic Kidney Disease

Javier A Neyra; Lakhmir S Chawla

doi:10.1016/j.ccc.2020.11.013

Acute Kidney Disease to Chronic Kidney Disease

Crit Care Clin. 2021 Apr;37(2):453-474. doi: 10.1016/j.ccc.2020.11.013. Epub 2021 Feb 13.

Authors

Javier A Neyra¹, Lakhmir S Chawla²

Affiliations

¹ Department of Internal Medicine, Division of Nephrology, Bone and Mineral Metabolism, University of Kentucky Medical Center, 800 Rose Street, MN668, Lexington, KY 40536, USA. Electronic address: javier.neyra@uky.edu.
² Department of Medicine, Veterans Affairs Medical Center, 3350 La Jolla Village Drive, San Diego, CA 92161, USA.

PMID: 33752866
DOI: 10.1016/j.ccc.2020.11.013

Abstract

Acute kidney injury (AKI) and chronic kidney disease are common interconnected syndromes that represent a public health problem. Acute kidney disease (AKD) is defined as the post-AKI status of acute or subacute kidney damage/dysfunction manifested by persistence of AKI beyond 7 to 90 days after the initial AKI diagnosis. Limited clinical data exist regarding AKD epidemiology but its incidence is observed in ∼25% of AKI survivors. Useful risk-stratification tools to predict risk of AKD and its prognosis are needed. Interventions on fluid management, nephrotoxic exposure, and follow-up care hold promise to ameliorate the burden of AKD and its complications.

Keywords: AKD; AKI; Acute kidney disease; Acute kidney injury; CKD; Chronic kidney disease; Kidney recovery.

Publication types

Review

MeSH terms

Acute Disease
Acute Kidney Injury* / diagnosis
Acute Kidney Injury* / epidemiology
Acute Kidney Injury* / etiology
Humans
Incidence
Prognosis
Renal Insufficiency, Chronic* / complications
Renal Insufficiency, Chronic* / epidemiology
Renal Insufficiency, Chronic* / therapy
Risk Factors