A retrospective study comparing interventions by oncology and non-oncology pharmacists in outpatient chemotherapy

Cancer Rep (Hoboken). 2021 Aug;4(4):e1371. doi: 10.1002/cnr2.1371. Epub 2021 Mar 19.

Abstract

Background: The differences in the clinical pharmacy services (CPS) provided by oncology and non-oncology pharmacists have not been sufficiently explained.

Aim: This study aimed to demonstrate the differences in direct CPS provided by oncology and non-oncology pharmacists for patients and physicians, and to assess the potential impact of these services on medical costs.

Methods: We retrospectively examined CPS provided by oncology and non-oncology pharmacists for outpatients who underwent chemotherapy between January and December 2016.

Results: In total, 1177 and 1050 CPS provided by oncology and non-oncology pharmacists, respectively, were investigated. The rates of interventions performed by oncology and non-oncology pharmacists for physicians-determined treatment were 18.5% and 11.3%, respectively (p < .001). The rates of oncology and non-oncology pharmacist interventions accepted by physicians were 84.6 and 78.8%, respectively (p = .12). Level 4 and Level 5 interventions accounted for 64.6% of all oncology pharmacist interventions and 53.0% of all non-oncology pharmacist interventions (p = .03). The rates of improvement in symptoms from adverse drug reactions among patients resulting from interventions by oncology and non-oncology pharmacists were 89.4 and 72.1%, respectively (p = .02). Conservative assessments of medical cost impact showed that a single intervention by an oncology and by a non-oncology pharmacist saved ¥6355 and ¥3604, respectively.

Conclusion: The results of the present study suggested that CPS by oncology pharmacists enable safer and more effective therapy for patients with cancer and indirectly contribute to reducing health care fees.

Keywords: chemotherapy; clinical pharmacy services; interventions; pharmacist; retrospective study.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Ambulatory Care / organization & administration
  • Ambulatory Care / statistics & numerical data
  • Antineoplastic Agents / administration & dosage*
  • Antineoplastic Agents / adverse effects
  • Drug-Related Side Effects and Adverse Reactions / etiology
  • Drug-Related Side Effects and Adverse Reactions / prevention & control
  • Female
  • Humans
  • Male
  • Medical Oncology / organization & administration
  • Medical Oncology / statistics & numerical data*
  • Medication Therapy Management / organization & administration
  • Medication Therapy Management / statistics & numerical data*
  • Middle Aged
  • Neoplasms / drug therapy*
  • Outpatient Clinics, Hospital / organization & administration
  • Outpatient Clinics, Hospital / statistics & numerical data
  • Pharmacists / organization & administration
  • Pharmacists / statistics & numerical data*
  • Pharmacy Service, Hospital / organization & administration
  • Pharmacy Service, Hospital / statistics & numerical data
  • Professional Role
  • Retrospective Studies
  • Young Adult

Substances

  • Antineoplastic Agents